DL-Dithiothreitol CAS 3483-12-3 Buffer Chemical White Solid Antioxidant

Product Description:

Product Name: DL-Dithiothreitol CAS 3483-12-3

Synonyms:

DL-1,4-Dithiothreitol;

DL-1,4-Dimercapto-2,3-dihydroxybutane;

1,4-Disulfanylbutane-2,3-diol;

Chemical & Physical Properties:

Appearance: white solid

Assay :≥99.0%

Density: 1.04g/cm3

Melting point:41-44℃

Boiling point:125℃

Flash point:174.2℃

Solubility:H2O: 50 mg/mL, clear, colorless

Water Solubility:freely soluble

Storage conditions: -20℃ (or 4℃ short term).

Application:

DL-1,4-Dithiothreitol has antioxidant effects, it can protect the reducing groups on enzyme molecules, maintain a reducing environment, and stabilize enzyme activity. 1,4-Disulfanylbutane-2,3-diol also contains certain RNA enzyme inhibitors, which have the effect of inhibiting RNA enzyme activity. It has a similar effect to mercaptoethanol, but DL-1,4-Dimercapto-2,3-dihydroxybutane has a much less irritating odor and lower toxicity than mercaptoethanol. Moreover, when the concentration of DTT is 7 times lower than that of mercaptoethanol, the two effects are similar. But the price of DL-Dithiothreitol is slightly higher. Used as a protein amino acid protectant and for the cleavage and sequence analysis of protein disulfide bonds;

Threo-1,4-Dimercapto-2,3-butanediol is a small molecule organic reducing agent with the chemical formula C4H10O2S2, mainly used in the field of biotechnology as a protein lysis reagent. The most widely used method for synthesizing dithiothreitol is to use threitol as the raw material, first oxidize it with potassium permanganate, then obtain a thio intermediate under the action of thioacetic acid, and finally hydrolyze the thio intermediate to obtain dithiothreitol;

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