Tocofersolan CAS 9002-96-4 Pharmaceutical Excipients C39H66O8

Product Description:

Product Name: Tocofersolan CAS NO: 9002-96-4

Synonyms:

d-alpha-tocopheryl polyethylene glycol succinate;

alpha-(4-((3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2h-1-benzopyran-6-yl)oxy)-1,4-dioxobutanol poly(ethylene glycol) succinate;tocofersolan;

tocopherosolan;

Chemical & Physical Properties:

Appearance: Clear, colorless solid

Assay :≥99.0%

Density: 1.01g/cm3

Boiling Point: 662.7℃ at 760mmHg

Melting Point: 34-38℃

Flash Point: 195.4℃

Refractive Index: 1.496

Stability: Stable under normal temperatures and pressures.

Storage Condition: 2-8℃

Safety Information:

WGK Germany: 2

RTECS: TR1581200

Tocofersolan (INN) or tocophersolan is a synthetic water-soluble version of vitamin E. Natural forms of vitamin E are fat soluble, but not water-soluble. Tocofersolan is polyethylene glycol derivative of α-tocopherol that enables water solubility.

Tocofersolan is used as a vitamin E supplement or to treat vitamin E deficiency in individuals who cannot absorb fats due to disease. On 24 July 2009 the European Medicines Agency approved tocofersolan under the trade name Vedrop 50mg/ml oral solution for the treatment of vitamin E deficiency due to digestive malabsorption in paediatric patients suffering from congenital or hereditary chronic cholestasis, from birth (in term newborns) to 16 or 18 years of age (depending on the region).

Tocofersolan is also used in cosmetics and pharmaceuticals as an antioxidant.

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