Pharmaceutical Intermediates 2S -1- Chloroacetyl -2-Pyrrolidine Carbonitrile CAS 207557-35-5

Product Description:

Product Name: (2S)-1-(Chloroacetyl)-2-pyrrolidine carbonitrile CAS NO: 207557-35-5

Synonyms:

1-chloroacetyl-2-(S)-pyrrolidinecarbonitrile;

(2S)-1-Chloroacetylpyrrolidine-2-carbonitrile;

Chemical & Physical Properties:

Appearance : Off-white to light yellow powder

Assay: NLT98.5%

Melting point: >60°C (dec.)

Flash Point: 173.43℃

Boiling Point:363.15℃ at 760 mmHg

Density: 1.273 g/cm3

Vapor Pressure: 0mmHg at 25°C

Refractive Index: 1.519

PSA: 44.10000

LogP: -0.62

Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly).

Safety Information:

HS Code: 2933990090

Safety Statements: S26-S24/25

WGK Germany : 3

Risk Statements:R22

Hazard Codes Xn

Application:

1. Vildagliptin intermediate; 1-Chloroacetyl-2-(S)-cyanopyrrolidine is used in the preparation of Vildagliptin.

2. (2S)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile is a key intermediate for dipeptidyl peptidase IV inhibitor Vildagliptin.

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