(R)-3-BOC-Aminopiperidin e CAS 309956-78-3

Product Description:

Product Name: (R)-3-BOC-Aminopiperidin e CAS NO:309956-78-3

Synonyms:

(R)-3-amino-3-N-Boc-piperidin e;

(R)-piperidin-3-yl-carbamic acid Tert-butyl ester;

(3R)-3-[(Tert-Butoxycarbonyl)amino]piperidin e;

Chemical & Physical Properties:

Appearance : White or off-white crystalline powder

Assay : No less than 99%

Density: 1.02g/cm3

Melting point:121-125℃

Boiling point:304.8℃ at 760 mmHg

Flash point: 138.2℃

Vapour Pressure: 0.0±2.0 mmHg at 25°C

Index of Refraction: 1.479

Solubility: Soluble in methanol and ethanol.

optical activity: [α]22/D +3.2°, c = 0.5 in DMF

Category: N-BOC;pharmacetical;Piperidin e;Piperidin e Series;Piperidin es;Intermediates

Safety Information:

Safety Statements: S66/39/61/29/36

Risk Statements: 37/38-41-50

Hazard Codes: Xi,N

HS Code: 2933990090

Application:

1. Linagliptin intermediate; (R)-Tert-butyl piperidin-3-ylcarbamate is used to synthesize and produce the hypoglycemic agent lilalidine.

2. Alogliptin Benzoate side chain; (R)-3-(Boc-Amino)piperidin e is Boc protected (R)-3-Aminopiperidin e (A627920, Dihydrochloride salt) which has been used as a reactant for the preparation of dipeptidyl peptidase IV inhibitors derived from Alogliptin.

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