2'-Hydroxy-3'-aminobiphenyl-3-carboxylic Acid CAS 376592-93-7

Product Description:

Product Name: 3'-Amino-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid CAS NO: 376592-93-7

Synonyms:

2'-Hydroxy-3'-aminobiphenyl-3-carboxylic acid;

[1,1'-Biphenyl]-3-carboxylic acid, 3'-amino-2'-hydroxy-;

Chemical & Physical Properties:

Appearance : Brown solid

Assay : ≥98.0%

Density: 1.364g/cm3

Melting point: ＞175℃

Boiling Point: 474.8 ℃ at 760 mmHg

Flash Point: 241.0 ℃

Refractive Index: 1.686

Pka: 3.99±0.10(Predicted)

Vapor Pressure: 0.0mmHg at 25°C

PSA: 83.55000

LogP:2.92080

Solubility: DMSO (Slightly), Methanol (Slightly, Heated).

Category: Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;

Safety Information:

HS Code: 2922509090

GHS Classification

Pictogram(s): Irritant

Signal:Warning

GHS Hazard Statements:

The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Precautionary Statement Codes:

P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501

Storage:Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

Application: Eltrombopag olamine Intermediate;

3’-Amino-2’-Hydroxy-[1,1’]Biphenyl-3-carboxylic Acid is used in the synthesis of monoethanolamine salts. A hydrazine cleavage product from Eltrombopag, an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.

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Inventory Status : In Stock.

We can provide 3'-amino-2'-hydroxy-biphenyl-3-carboxylic acid COA (certificate of analysis), CAS NO: 376592-93-7 MOA (Method of Analysis), 3-(3-amino-2-hydroxyphenyl)benzoic acid ROS (Route of synthesis), 3'-Amino-2'-hydroxy-3-biphenylcarboxylic acid MSDS (Material Safety Data Sheet) and other support for you !

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