1-Piperidinecarboxylicacid,3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-,1,1-dimethylethylester,(3R)

Product Description:

Product Name: 1-Piperidinecarboxylicacid,3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-,1,1-dimethylethylester,(3R)- CAS 1022150-11-3

Synonyms:

N-Boc-Ibrutinib;

(R)-3-[4-Amino-3-(4-phenoxy-phenyl)-pyrazolo[3,4-d]pyrimidin-1-yl]-piperidi ne-1-carboxylicacidtert-butylester;

3-[4-Amino-3-(4-phenoxy-phenyl)-pyrazolo[3,4-d]pyrimidin-1-yl]-piperidi ne-1-carboxylic acid tert-butyl ester;

Chemical & Physical Properties:

Appearance : White to off-white powder.

Assay : ≥99.0%

Density: 1.31g/cm³

Melting point: 103-106℃

Boiling Point: 673.9℃ at 760 mmHg

Flash Point: 361.4℃

Refractive Index: 1.662

Vapor Pressure: 0.0mmHg at 25°C

PSA: 108.39000

LogP: 5.95890

Pka: 4.09±0.30(Predicted)

Solubility: DMSO (Slightly), Ethyl Acetate (Slightly)

Category: Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Intermediates;

Safety Information:

HS Code: 2933599090

Storage:Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

Application:

(R)-tert-Butyl3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidi ne-1-carboxylate is an impurity of Ibrutinib, which is a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.

Our factory manufacture’s (R)-tert-Butyl3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidi ne-1-carboxylate, mature technology, stable output, quality assurance.

Inventory Status : In Stock.

We can provide tert-butyl (R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidi ne-1-carboxylate COA (certificate of analysis), tert-butyl (3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3.4-d]pyrimidin-1-yl]piperidi ne-1-carboxylate MOA (Method of Analysis), ROS (Route of synthesis),CAS 1022150-11-3 MSDS (Material Safety Data Sheet) and other support for you !

we can supply Ibrutinib And Intermediates:

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Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.