(S)-1-Boc-3-hydroxypiperidine CAS NO 143900-44-1

Product Description:

Product Name: (S)-1-Boc-3-hydroxypiperidine CAS NO:143900-44-1

Synonyms:

(S)-1-Tert-Butoxycarbonyl-3-Hydroxypiperidine;

(S)-3-Hydroxy-Piperidi ne-1-Carboxylicacidtert-Butylester;

(S)-3-Hydroxy-1-(Tert-Butoxycarbonyl)Piperidi ne;

(S)-1-Boc-3-Piperidinol;

(S)-N-(Tert-Butoxycarbonyl)-3-Hydroxypiperidinehydrochloride;

(S)-N-Boc-3-Hydroxypiperidine;

(S)-Tertbutyl-3-Hydroxypiperidine-1-Carboxylate;

(S)-1-(tert-Butoxycarbonyl)-3-hydroxypiperidine;

Chemical & Physical Properties:

Appearance : White to Pale Yellow powder.

Assay : ≥99.0%

Density: 1.107g/cm3

Melting point: 34-40℃

Boiling Point: 292.3℃ at 760 mmHg

Flash Point: 110℃

Refractive Index: 1.495

Vapor Pressure: 0.0mmHg at 25°C

PSA: 49.77000

LogP: 1.31610

Pka: 14.74±0.30(Predicted)

Solubility: Soluble in methanol.

Category: Piperidines;Piperazine; Pharmaceutical/API Drug Intermediates;

Safety Information:

HS Code: 2933399090

Safety Statements: S26

Risk Statements:R36/37/38

Hazard Codes: Xi

Storage:Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

Application:

1,1-dimethylethyl (3S)-3-hydroxypiperidine-1-carboxylate is an important chiral intermediate for the synthesis of ibrutinib, an anticancer drug targeting B-cell malignancies. Synthesis of pharmaceutical intermediates including ibrutinib, the API of the newly approved drug Imbruvica, for the treatment of lymphoma.

Our factory manufacture’s (3S)-1-(tert-Butyloxycarbonyl)piperidi ne-3-ol , mature technology, stable output, quality assurance.

Inventory Status : In Stock.

We can provide (S)-3-hydroxy-N-Boc-piperidi ne COA (certificate of analysis), (S)-1-BOC-Piperidin-3-ol MOA (Method of Analysis), (3S)-1-(tert-Butoxycarbonyl)-3-hydroxypiperidine ROS (Route of synthesis), (S)-N-tert-Butoxycarbonyl-3-hydroxypiperidine MSDS (Material Safety Data Sheet) and other support for you !

we can supply Ibrutinib And Intermediates:

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Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.