3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine CAS NO 1022150-12-4

Product Description:

Product Name: 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine CAS NO:1022150-12-4

Synonyms:

3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine;

1H-Pyrazolo[3,4-d]pyrimidin-4-amine,3-(4-phenoxyphenyl)-1-[(3R)-3-piperidinyl]-;

Chemical & Physical Properties:

Appearance : White to Pale Yellow powder.

Assay : ≥99.0%

Density: 1.4g/cm3

Melting point:133-136℃

Boiling Point: 626.3℃ at 760 mmHg

Flash Point: 332.6℃

Refractive Index: 1.731

Vapor Pressure: 0.0mmHg at 25°C

PSA: 90.88000

LogP: 4.70230

Pka: 9.00±0.10(Predicted)

Solubility: DMSO (Slightly), Methanol (Slightly).

Category: Piperidines; Chiral Molecules; Pharmaceutical/API Drug Intermediates;

Safety Information:

HS Code: 2933399090

Storage:Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

Application:

1. (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is an intermediate used to prepare pyrazolo-pyrimidine compounds as inhibitors of Bruton's tyrosine kinase. It is also an intermediate for Ibrutinib derivatives.

2. Btk inhibitor 1 R enantiomer is a pyrazolo[3,4-d]pyrimidine derivative as a BTK kinase inhibitor.

3. (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is an intermediate of selective, irreversible Btk inhibitor Ibrutinib (PCI-32765).

Our factory manufacture’s (3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine , mature technology, stable output, quality assurance.

Inventory Status : In Stock.

We can provide 3-(4-phenoxyphenyl)-1-(3R)-3-piperidinyl-1H-Pyrazolo[3,4-d]pyrimidin-4-amine COA (certificate of analysis), MOA (Method of Analysis), ROS (Route of synthesis), CAS 1022150-12-4 MSDS (Material Safety Data Sheet) and other support for you !

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FAQ:

Q1: How to confirm the Product Quality before placing orders?

A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

Q2: How about delivery leadtime?

A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)

Q3:Is there a discount?

A:Different quantity has different discount.

Q4: How do you treat quality complaint?

A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

Q5. How about the packing?

Usually we provide the packing as 25 kg / bag or carton. Of course, if you have special requirements on them, we will according to you.

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Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.