5-amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile CAS NO 330792-70-6

Product Description:

Product Name: 5-amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile CAS NO: 330792-70-6

Synonyms:

3-Amino-4-cyano-5-(4-phenoxyphenyl)pyrazole;

1H-Pyrazole-4-carbonitrile,3-aMino-5-(4-phenoxyphenyl)-;

Chemical & Physical Properties:

Appearance : Light yellow to off-white powder.

Assay : ≥99.0%

Density: 1.37g/cm3

Melting point: N/A

Boiling Point: 585.3℃ at 760 mmHg

Flash Point: 307.8℃

Refractive Index: 1.699

Vapor Pressure: 0.0mmHg at 25°C

PSA: 88.45000

LogP: 3.25298

Pka: 10.83±0.50(Predicted)

Solubility: DMSO (Slightly),

Category: Pyrazole ;Pharmaceutical/API Drug Intermediates; Standards;

Safety Information:

HS Code: 2933199090

Signal Word: Warning

Hazard Statements: H302,H312,H315,H319,H335

Precautionary Statements: P260,P280,P301+P312,P302+P352,P304+P340

RIDADR: NONH for all modes of transport

Storage:Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

Application:

3-Amino-4-cyano-5-(4-phenoxyphenyl)pyrazole has been used as a reactant in the preparation of ring-fused pyrazole derivatives to be used a inhibitors of lymphocyte-specific kinase (Lck).

5-amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile is an intermediate of Ibrutinib (PCI-32765).

it is a heterocyclic intermediate that typically used in the preparation of ACP-196, a selective second-generation BTK inhibitor.

Our factory manufacture’s 3-amino-5-(4-phenoxyphenyl)-1H-Pyrazole-4-carbonitrile, mature technology, stable output, quality assurance.

Inventory Status : In Stock.

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