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Home > products > Pharmaceutical Intermediates > 4-Nitrobenzyl (2S,4S)-4-acetylthio-2-[[N-sulfamoyl-N-(tert-butoxycarbonyl)amino]methyl]pyrrolidine-1-carboxylate CAS 491

4-Nitrobenzyl (2S,4S)-4-acetylthio-2-[[N-sulfamoyl-N-(tert-butoxycarbonyl)amino]methyl]pyrrolidine-1-carboxylate CAS 491

Product Details

Place of Origin: China

Brand Name: Sunshine

Certification: ISO,COA

Model Number: 491878-06-9

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Price: Negotiation

Packaging Details: Aluminum Foil Bag, Drum

Delivery Time: 7-15 days

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Highlight:
CAS NO::
491878-06-9
Appearance::
Off-white To Light Yellow Powder
Molecular Formula::
C20H28N4O9S2
Molecular Weight::
532.588
EINECS NO::
610-446-3
MDL NO::
MFCD14635210
CAS NO::
491878-06-9
Appearance::
Off-white To Light Yellow Powder
Molecular Formula::
C20H28N4O9S2
Molecular Weight::
532.588
EINECS NO::
610-446-3
MDL NO::
MFCD14635210
4-Nitrobenzyl (2S,4S)-4-acetylthio-2-[[N-sulfamoyl-N-(tert-butoxycarbonyl)amino]methyl]pyrrolidine-1-carboxylate CAS 491

Product Description:

Product Name: 4-Nitrobenzyl (2S,4S)-4-acetylthio-2-[[N-sulfamoyl-N-(tert-butoxycarbonyl)amino]methyl]pyrrolidine-1-carboxylate CAS NO:491878-06-9

 

Synonyms:

ACS-PNZ-PYRROLIDYL-(BOC)-NSO2NH2;

 

Chemical & Physical Properties:

Appearance: off-white to light yellow powder

Assay :≥98.0%

Density:1.45 g/cm3

Boiling Point:686.8℃ at 760 mmHg

Melting Point:124-132℃

Flash Point:369.2℃

 

 

(4-nitrophenyl)methyl (2S,4S)-4-acetylsulfanyl-2-[[(2-methylpropan-2-yl)oxycarbonyl-sulfamoylamino]methyl]pyrrolidine-1-carboxylate is used to synthesize the penem antibiotic Doripemen.

Doripenem is a new type of carbapenem antibiotic developed by Shionoyoshi Company of Japan. It has a broad antibacterial spectrum and is stable to most β-lactamases, including penicillinase, cephalosporinase and extended-spectrum β-lactamase. Amidases (ESBLs).

 

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