Croscarmellose Sodium CAS 74811-65-7

Product Description:

Product Name: Croscarmellose Sodium CAS NO: 74811-65-7

Synonyms:

Croscarmellose natrium;

Croscarmellose sodium;

Cross-linked carboxymethylcellulose sodium;

Chemical & Physical Properties:

Appearance: white to grayish white powder

Assay :≥99.0%

Density: Bulk density (g/cc) 0.48

Solubility: Practically insoluble in ace-tone, in anhydrous ethanol and in toluene.

Croscarmellose natrium is used as Disintegrant in Capsules, Tablet and Granule Formulations. Croscarmellose sodium is used in oral pharmaceutical formulations as a disintegrant for capsules,tablets, and granules.

In tablet formulations, croscarmellose sodium may be used in bothdirect-compressionandwet-granulationprocesses.Whenused in wet granulations, the croscarmellose sodium should be added in both the wet and dry stages of the process (intra- and extragranularly) so that the wicking and swelling ability of the disintegrant is best utilized. Croscarmellose sodium at concentrations up to 5% w/w may be used as a tablet disintegrant, although normally 2% w/w is used in tablets prepared by direct compression and 3% w/w in tablets prepared by a wet-granulation process.

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