Product Details
Place of Origin: China
Brand Name: Sunshine
Certification: ISO,COA
Model Number: 1446321-46-5
Payment & Shipping Terms
Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: Aluminum Foil Bag, Drum
Delivery Time: 7-15 days
Payment Terms: T/T, L/C, D/A, Western Union
Supply Ability: TON
CAS NO:: |
1446321-46-5 |
Appearance:: |
White To Off-white Solid Powder |
Molecular Formula:: |
C19H19N3O3 |
Molecular Weight:: |
337.372 |
EINECS NO:: |
N/A |
MDL NO:: |
MFCD29053764 |
CAS NO:: |
1446321-46-5 |
Appearance:: |
White To Off-white Solid Powder |
Molecular Formula:: |
C19H19N3O3 |
Molecular Weight:: |
337.372 |
EINECS NO:: |
N/A |
MDL NO:: |
MFCD29053764 |
Product Description:
Product Name: voxelotor CAS NO:1446321-46-5
Synonyms:
2-hydroxy-6-([2-[1-(propan-2-yl)-1H-pyrazol-5-yl]pyridin-3-yl]meth-oxy)benzaldehyde;
GBT 440; GTx-011;
Chemical & Physical Properties:
Appearance: White to off-white solid powder
Assay :≥98.0%
Density:1.23g/cm3
Boiling Point: 539.2℃ at 760 mmHg
Flash point:279.9℃
Solubility: Soluble in DMSO
Voxelotor, also known as GBT-440, is a hemoglobin S allosteric modulator. GBT440 Inhibits Sickling of Sickle Cell Trait Blood Under In Vitro Conditions Mimicking Strenuous Exercise. GBT440 increases haemoglobin oxygen affinity, reduces sickling and prolongs RBC half-life in a murine model of sickle cell disease. GBT440 increases haemoglobin oxygen affinity, reduces sickling and prolongs RBC half-life in a murine model of sickle cell disease.
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