Hydrocortisone CAS 50-23-7 Drug Product Intermediate C21H30O5

Product Description:

Product Name: Hydrocortisone CAS NO: 50-23-7

Synonyms:

Alacort;

Hycort;

11,17,21-trihydroxy-pregn-4-ene-3,20-dione;

Chemical & Physical Properties:

Appearance: Crystalline white powder

Assay :≥98.0%

Density: 1.28g/cm3

Boiling Point: 566.4℃ at 760 mmHg

Melting Point: 213-220℃

Flash Point: 310.4℃

Refractive Index: 1.594

Stability: Stable, but may be light sensitive. Incompatible with strong oxidizing agents.

Storage Condition: -20℃

Water Solubility: 319.7mg/L(25℃)

Safety Information:

HS Code: 2937210000

Hazard Codes: Xn

Hazardous Substances Data: 50-23-7(Hazardous Substances Data)

RTECS: GM8925000

Risk Statements: R62; R63

Safety Statements: S36/37-S45

Toxicity: LD50 subcutaneous in mouse: > 500mg/kg

WGK Germany : 3

Cortisol, or Hydrocortisone, is a s teroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism. ChEBI: A C21-s teroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy groups at positions 11, 17 and 21. Cortisol is a corticos teroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immun responses.

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