3-hydroxypyrazine-2-carboxaMide CAS 55321-99-8

Product Description:

Product Name: 3-hydroxypyrazine-2-carboxaMide CAS NO: 55321-99-8

Synonyms:

2-oxo-1H-pyrazine-3-carboxamide;

Pyrazinecarboxamide, 3,4-dihydro-3-oxo-;

Chemical & Physical Properties:

Appearance: Crystalline powder or Solid

Assay :≥99.0%

Density: 1.63±0.1 g/cm3 (Predicted)

Melting point:ca 270℃

PKa: 10.69±0.40 (Predicted)

Safety Information:

Signal:Warning

Hazard Statements: H315/319/335

Precautionary Statement Codes: P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501

Risk Statements 36/37/38

Safety Statements 26-37

HS Code 29339900

3-Hydroxypyrazine-2-carboxamide (T-1105) is reported as an antiviral compound with broad activity against influenza virus and diverse RNA viruses. Its ribose-5’-triphosphate is the active metabolite, and it is recognized by virus RNA polymerase as a substrate competing with guanosine 5'-triphosphate (GTP), giving inhibition of viral RNA synthesis. For your reference, an antiviral agent favipiravir (T-705) [F1296], is an analog adding the 6-fluoro atom. (The product is for research purpose only.)

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