![N1-[2-(Dimethylamino)ethyl]-5-methoxy-N1-methyl-N4-[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]-1,2,4-benzenetriamine CAS](/images/load_icon.gif){kind=icon}
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Product Details
Place of Origin: China
Brand Name: Sunshine
Certification: ISO,COA
Model Number: 1421372-66-8
Payment & Shipping Terms
Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: Aluminum Foil Bag, Drum
Delivery Time: 7-15 days
Payment Terms: T/T, L/C, D/A, Western Union
Supply Ability: TON
CAS NO:: |
1421372-66-8 |
Appearance :: |
Yellow Solid |
Molecular Formula:: |
C25H31N7O |
Molecular Weight:: |
445.56 |
EINECS NO:: |
N/A |
MDL NO:: |
MFCD28167800 |
CAS NO:: |
1421372-66-8 |
Appearance :: |
Yellow Solid |
Molecular Formula:: |
C25H31N7O |
Molecular Weight:: |
445.56 |
EINECS NO:: |
N/A |
MDL NO:: |
MFCD28167800 |
Product Description:
Product Name: N1-[2-(Dimethylamino)ethyl]-5-metho xy-N1-methyl-N4-[4-(1-methyl-1 H-indol-3-yl)-2-pyrimidinyl]-1,2,4-benzenetriamine CAS NO: 1421372-66-8
Synonyms:
AZD9291 intermediate 3;
1,2,4-Benzenetriamine, N-[2-(dimethylamino)ethyl]-5-metho xy-N-methyl-N-[4-(1-methyl-1H -indol-3-yl)-2-pyrimidinyl]-;
N-[2-(Dimethylamino)ethyl]-5-metho xy-N-methyl-N-[4-(1-methyl-1H -indol-3-yl)-2-pyrimidinyl]-1,2,4-benzenetriamine;
N1-[2-(diMethylaMino)ethyl]-5-Metho xy-N 1-Methyl-N4-[4-(1-Methyl-1H -indol-3-yl)-2-pyriMidinyl]benzene-1,2,4-triamine;;
Chemical & Physical Properties:
Appearance : Yellow Solid.
Assay : ≥99.0%
Mutated EGFR-IN-1 is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activating mutant and T790M resistance mutant.IC50 value:Target: Mutated EGFR inhibitorMore information can be found in Patent WO 2013014448 A1.2 - (2, 4, 5 - substituted -anilino) pyrimidine derivatives as egfr modulators useful for treating cancer.
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