Tert-Butyl (4R-cis)-6-formaldehydel-2,2-dimethyl-1,3-dioxane-4-acetate CAS 124752-23-4

Product Description:

Product Name: tert-Butyl (4R-cis)-6-formaldehydel-2,2-dimethyl-1,3-dioxane-4-acetate CAS NO:124752-23-4

Synonyms:

tert-butyl (3R,5S)-6-oxo-3,5-dihydroxy-3,5-O-isopropylidenehexanoate;

tert-butyl 3,5-dideoxy-2,4-O-(1-methylethylidene)-L-erythro-hexuronate;

tert-butyl 2-((4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate;

t-butyl (3R,5S)-3,5-isopropylidenedioxy-6-oxohexanoate;

t-butyl 2-[(4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate;;

Chemical & Physical Properties:

Appearance :Off-white solid

Assay :≥99.0%

Density:1.073 g/cm3

Boiling Point: 320.3℃ at 760 mmHg

Flash Point:140.6℃

tert-butyl [(4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate is used to Rosuvastatin intermediate.

Rosuvastatin calcium is an anti-hyperlipidemic drug and belongs to the HMG-CoA reductase inhibitor. It was successfully developed by AstraZeneca in the United Kingdom and is suitable for the treatment of various lipid abnormalities, including hypercholesterolemia and mixed lipids Qualitative abnormalities and simple hypertriglyceridemia. Rosuvastatin calcium is the statin drug with the strongest lipid-lowering effect and the most comprehensive lipid-lowering effect among the currently listed lipid-lowering drugs. It has better lowering of low-density lipoprotein cholesterol and Improve the role of high-density lipoprotein.

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