(5-bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone CAS 461432-22-4

Product Description:

Product Name: (5-bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone CAS NO:461432-22-4

Synonyms:

5-bromo-2-chloro-4'-ethoxybenzophenone;

Chemical & Physical Properties:

Appearance :white powder

Assay :≥99.0%

Density:1.437g/cm3

Boiling Point:439.16℃ at 760 mmHg

Flash Point:219.4℃

Dapagliflozin intermediate.

Dapagliflozin works by inhibiting sodium-glucose transporter 2 (SGLT2), a protein in the kidney that allows glucose to be reabsorbed into the blood. This allows excess glucose to be eliminated from the body through urine, thereby improving blood sugar control without increasing insulin secretion. The use of this drug requires patients with normal renal function, and patients with moderate to severe renal insufficiency should not use the drug. This product alone or in combination with metformin, pioglitazone, glimepiride, insulin and other drugs can significantly reduce HbA1c and fasting blood glucose in patients with type 2 diabetes. The incidence of adverse reactions is similar to that of placebo. The risk of hypoglycemia is low and can be reduced. body weight. The efficacy of dapagliflozin is equivalent to that of several new hypoglycemic drugs such as dipeptidyl peptidase inhibitors, and it can slightly lower blood pressure and weight.

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