Product Details
Place of Origin: China
Brand Name: Sunshine
Certification: ISO,COA
Model Number: 1448326-33-7
Payment & Shipping Terms
Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: Aluminum Foil Bag, Drum
Delivery Time: 7-15 days
Payment Terms: T/T, L/C, D/A, Western Union
Supply Ability: TON
CAS NO:: |
1448326-33-7 |
Appearance :: |
White Powder |
Molecular Formula:: |
C13H10BrCl2FN2O |
Molecular Weight:: |
380.04 |
EINECS NO:: |
N/A |
MDL NO:: |
MFCD28099329 |
CAS NO:: |
1448326-33-7 |
Appearance :: |
White Powder |
Molecular Formula:: |
C13H10BrCl2FN2O |
Molecular Weight:: |
380.04 |
EINECS NO:: |
N/A |
MDL NO:: |
MFCD28099329 |
Product Description:
Product Name: 3-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-bromopyridin-2-amine CAS NO:1448326-33-7
Synonyms:
5-Bromo-3-[(1S)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-2-pyridinamine;
(S)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine;
Chemical & Physical Properties:
Appearance :white powder
Assay :≥99.0%
Density:1.6g/cm3
Boiling Point:423.4℃ at 760 mmHg
Flash Point:209.9℃
Crizotinib intermediate.
Crizotinib is a dual-acting small molecule tyrosine kinase receptor inhibitor targeting mesenchymal-epithelial transition (MET) and ALK. Its target of action in NSCLC is ALK tyrosine Acid kinase receptor. Similar to the EGFR inhibitor gefitinib, crizotinib inhibits the activation of kinase by inhibiting the binding of ALK kinase and ATP in NSCLC and the autophosphorylation after the combination of the two, thereby reducing kinase activity and playing an anti-tumor effect .
If you are interested in our products or have any questions, please feel free to contact us!
Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.
