(S)-3-Amino-3-phenyl Propionic Acid Methyl Ester Hydrochloride CAS 144494-72-4

Product Description:

Product Name: (S)-3-Amino-3-phenyl propionic acid methyl ester hydrochloride CAS NO: 144494-72-4

Synonyms:

3-amino-3-phenylpropionic acid methyl ester hydrochloride;

methyl 3-amino-3-phenylpropionate hydrochloride;

methyl D,L-3-amino-3-phenylpropionate.HCl;

Chemical & Physical Properties:

Appearance: Off-white or white powder

Assay :≥99.0%

Boiling Point: 317.4℃ at 760 mmHg

Flash Point: 145.8℃

Vapor Pressure: 0.000283mmHg at 25℃

Safety Information:

Signal Word: Warning

Hazard Statements: H315; H319; H335

Precautionary Statements: P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

(BETAS) -beta-aminophenilate methyl hydrochloride is an intermediate of dapoxeti-ne, a short-acting selective serotonin reuptake inhibitor (SSRIs) that is currently the only drug approved by the FDA for the treatment of premature ejaculation. It is characterized by on-demand oral administration, rapid onset, short half-life, rapid absorption of 1.5 hours to reach the peak, Chemicalbook primary and secondary PE has similar efficacy. Dapoxeti-ne hydrochloride, originally developed by Johnson & Johnson, was first approved in Finland and Sweden in February 2009 as a treatment for male premature ejaculation. Dapoxeti-ne hydrochloride was approved to be listed in China in 2010 under the trade name of Bilijin. So far, it has been approved for listing in more than 60 countries and regions, including China.

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