(R,R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol CAS 716-61-0

Product Description:

Product Name: (R,R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol CAS NO: 716-61-0

Synonyms:

D-(-)-THREO-2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL;

(1R,2R)-2-amino-1-(4-nitrophenyl)propane-1,3-diol;

Chemical & Physical Properties:

Appearance: Light yellow powder

Assay :≥98.0%

Density: 1.41 g/cm3

Boiling Point: 451.9℃ at 760 mmHg

Melting Point: 163-165℃

Flash Point: 227.1℃

Storage Condition: -20℃

Vapor Pressure: 0.0±1.2 mmHg at 25℃

Safety Information:

Safety Statement: S26

RIDADR: UN 3259

Risk Statements: R22; R36/37/38

Hazard Codes: Xn,T

Symbol: GHS07

Signal Word: Warning

Hazard Statements: H302-H315-H319-H335

Precautionary Statements: P261-P305 + P351 + P338

D-threo-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol is an impurity of Chlorampheni-col, a broad spectrum antibiotic agent obtained from cultures of the soil bacterium Streptomyces venezuelae. Chlorampheni-col base is the parent 4-nitrophenylpropylamine formed by the hydrolysis of the dichloroacetamide of chlorampheni-col and is a degradation product commonly encountered with commercial production of chlorampheni-col. Chlorampheni-col base has no antibiotic activity but has played an integral role in the synthesis and SAR of new generation antibiotics, notably thiamphenicol and experimental analogues, bromamphenicol and methamphenicol.

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