Azetidin-3-ol,hydrochloride CAS 18621-18-6

Product Description:

Product Name: azetidin-3-ol,hydrochloride CAS NO: 18621-18-6

Synonyms:

3-hydroxyazetidine monohydrochloride;

3-Hydroxyazetidine-HCl;

3-Azetidinol Hydrochloride;

Chemical & Physical Properties:

Appearance: White crystal

Assay :≥98.0%

Boiling Point: 170.7℃ at 760 mmHg

Melting Point: 85-90℃

Flash Point: 120.4℃

Vapor Pressure: 0.464mmHg at 25℃

Storage Temp.: Room temperature

Water Solubility: Soluble in water, DMSO, methanol

Sensitive: Hygroscopic

Safety Information:

Hazard Codes: C; Xi; Xn

HS Code: 2933990090

Risk Statements: R36/37/38

Safety Statements: S26; S36/37/39

A useful intermediate in the synthesis of polypeptides. 3- hydroxyazacyclobutane hydrochloride is an important intermediate for the synthesis of baricotinib, which is finally obtained through multiple reactions. Baricotinib is approved in the European Union as a single agent or in combination with methotrexate for the treatment of adults with moderately to severely active rheumatoid arthritis who have inadequate or intolerant response to one or more anti-rheumatoid drugs (DMARDs). 3- hydroxyazacyclobutane hydrochloride is a hydrocarbon derivative and can be used as pharmaceutical intermediates.

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