White Crystalline Powder 5-fluorouracil CAS 51-21-8

Product Description:

Product Name: 5-fluorouracil CAS NO: 51-21-8

Synonyms:

5-fluoropyrimidine-2,4-dione;

Fluril;

Efudix;

Chemical & Physical Properties:

Appearance: White to nearly white crystalline powder

Assay :≥99.0%

Density: 1.53 g/cm3

Boiling Point: 401.4℃ at 760 mmHg

Melting Point: 278-286℃

Flash Point: 196.5℃

Refractive Index: 1.542

Water Solubility: 12.2 g/L 20℃

Stability: Stable. Light sensitive. Combustible. Incompatible with strong oxidizing agents, strong bases.

Storage Condition: Store at 0-5℃

Water Solubility: 12.2 g/L 20℃

Sensitive: Air sensitive

Safety Information:

Signal Word: Danger

Symbol: GHS06

Safety Statements: S36/37

HS Code: 2933599090

Packing Group: III

WGK Germany: 3

RTECS: YR0350000

RIDADR: UN 2811 6.1/PG 3

Risk Statements: R20/21/22

Hazard Class: 6.1

Hazard Codes: Xn,T,C,Xi

Hazard Declaration: H301; H412

Caution Statements: P273; P301 + P310

5-Fluoro Uracil is is an DNA/RNA synthesis inhibitor. It is used as a potent antitumor agent since it interrupts nucleotide synthetic by inhibiting thymidylate synthase.

1. It is used for biochemical studies and antitumor drugs.

2. It is the anti tumor drug, also used for synthesis of flucytosine. 5-fluorouracil can be used in the study of rice in the biochemical studies, ear differentiation, genetic metabolic measurement, plant growth development research.

3. It is used for the digestive system cancer, head and neck cancer, gynecological cancer, lung cancer, liver cancer, treatment of bladder cancer and skin cancer.

4. Antimetabolite antitumor drugs.

5. Anti tumor drugs. There is a certain effect on a variety of tumors such as digestive tract cancer, breast cancer, ovarian cancer, chorionic epithelial cancer, cervical cancer, hepatocellular carcinoma, bladder cancer, skin cancer (topical), leukoplakia (topical) etc. Adverse reactions mainly are bone marrow transplantation, digestive tract reaction, serious person can have diarrhea, local injection site phlebitis, a few of which have nervous system reactions such as cerebellar degeneration and ataxia. The course of medication should strictly check the blood.

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