C10H13N5O5 MFCD00010182 Guanosine CAS 118-00-3

Product Description:

Product Name: guanosine CAS NO: 118-00-3

Synonyms:

2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one;

Guanosin;

Guanosine Hydrate;

Chemical & Physical Properties:

Appearance: Off-white crystalline powder

Assay :≥99.0%

Density: 2.25g/cm3

Melting Point: 240℃

Boiling Point: 425.8℃ (rough estimate)

Flash Point: 423.1℃

Stability: Stable under normal temperatures and pressures

Storage Condition: Store at RT.

Solubility: 0.1 M NaOH: 0.1 g/mL, clear, slightly yellow

Vapor Pressure: 2.44E-25mmHg at 25℃

Safety Information:

Hazard Codes: T,Xi

Hazard Class: 6.1

HS Code: 29349990

Risk Statement: R25

RIDADR: UN 2811 6.1/PG 3

WGK Germany: 3

Packing Group: Ⅲ

Safety Statements: S24/25

Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine can be phosphorylated to become guanosine monophosphate (GMP), cyclic guanosine monophosphate (cGMP), guanosine diphosphate (GDP), and guanosine triphosphate (GTP). These forms play important roles in various biochemical processes such as synthesis of nucleic acids and proteins, photosynthesis, muscle contraction, and intracellular signal transduction (cGMP). When guanine is attached by its N9 nitrogen to the C1 carbon of a deoxyribose ring it is known as deoxyguanosine.

The antiviral drug aciclovir, often used in herpes treatment, and the anti-HIV drug abacavir, are structurally similar to guanosine.

Guanosine is required for an RNA splicing reaction in mRNA, when a "self-splicing" intron removes itself from the mRNA message by cutting at both ends, re-ligating, and leaving just the exons on either side to be translated into protein.

Guanosine with numbered carbons.

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