Product Details
Place of Origin: China
Brand Name: Sunshine
Certification: ISO,COA
Model Number: 1912445-55-6
Payment & Shipping Terms
Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: Aluminum Foil Bag, Drum
Delivery Time: 7-15 days
Payment Terms: T/T, L/C, D/A, Western Union
Supply Ability: TON
CAS NO:: |
1912445-55-6 |
Appearance:: |
Solid Or Powder |
Molecular Formula:: |
C20H23FN4O2 |
Molecular Weight:: |
370.42100 |
EINECS NO:: |
NA |
MDL NO:: |
MFCD31631584 |
CAS NO:: |
1912445-55-6 |
Appearance:: |
Solid Or Powder |
Molecular Formula:: |
C20H23FN4O2 |
Molecular Weight:: |
370.42100 |
EINECS NO:: |
NA |
MDL NO:: |
MFCD31631584 |
Product Description:
Product Name: BMS-986195 CAS NO: 1912445-55-6
Synonyms:
1H-Indole-7-carboxamide,5-fluoro-2,3-dimethyl-4-[(3S)-3-[(1-oxo-2-butyn-1-yl)amino]-1-piperidinyl]-;
(S)-4-(3-(2-Butynoylamino)piperidin-1-yl)-5-fluoro-2,3-dimethyl-1H-indole-7-carboxamide;
5-Fluoro-2,3-dimethyl-4-[(3S)-3-[(1-oxo-2-butyn-1-yl)amino]-1-piperidinyl]-1H-indole-7-carboxamide;
Chemical & Physical Properties:
Appearance: Solid or powder
Assay :≥98.0%
Density: 1.32±0.1 g/cm3 (Predicted)
PKa: 11.91±0.20 (Predicted)
Storage Conditions: -20℃
Branebrutinib (BMS-986195) is an effective BTK inhibitor with IC50 values of 0.1 nM, 0.9 nM, 1.5 nM, and 5 nM for BTK, TEC, BMX, and TXK, respectively. BMS-986195 is a potent, covalent, irreversible inhibitor of Bruton’s tyrosine kinase (BTK), with an IC50 of <1 nM.
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