4-Fluorobenzyl Bromide CAS 459-46-1

Product Description:

Product Name: 4-Fluorobenzyl bromide CAS NO: 459-46-1

Synonyms:

4-Fluoro-1-(bromomethyl)benzene;

α-Bromo-4-fluorotoluene;

1-(Bromomethyl)-4-fluorobenzene, alpha-Bromo-4-fluorotoluene;

Chemical & Physical Properties:

Appearance: Colorless to light yellow liquid

Assay :≥99.0%

Density: 1.517

Boiling Point: 85℃ (15 mmHg)

Flash Point: 74.8℃

Refractive Index: 1.5464-1.5484

Sensitive: Lachrymatory

Stability: Stable at room temperature in closed containers under normal storage and handling conditions. Reacts with water to form toxic fumes.

Storage Condition: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture.

Vapor Pressure: 0.143mmHg at 25℃

Safety Information:

Hazard Class: 8

Safety Statements: S26-S36/37/39-S45

HS Code: 2903999090

Packing Group: III

WGK Germany: 3

RIDADR: UN 3265

Risk Statements: R34; R36

Hazard Code: C

4-Fluorobenzyl Bromide is a substituted benzyl bromide reagent used in the preparation of wide range of biologically active compounds such as bronchodialators, neurochemicals and antibacterials. 4-Fluorobenzyl bromide is an important intermediate in organic chemistry. 4-Fluorobenzyl bromide can be used as alkylating reagent to participate in the alkylation reaction with sulfamic esters (R-O-SO2-NH2) in liquid-liquid phase transfer conditions, resulting in the preparation of the N-dialkyled products or the corresponding ethers by scission of the O-SO2 bond, depending on the nature of R.4-Fluorobenzyl bromide can be used for the synthesis of glycyrrhetinic acid (GA) derivatives, which are slow-binding inhibitors of tyrosinase and have inhibitory effects on melanogenesis.

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