[6-[benzoyl(methyl)amino]-5-methyl-3-pyridyl]boronic Acid CAS 446299-81-6

Product Description:

Product Name:[6-[benzoyl(methyl)amino]-5-methyl-3-pyridyl]boronic acid CAS 446299-81-6

Synonyms:

methyl-6-(N-methylbenzamido)pyridin-3-yl)boronic acid;

(S) - 6-chloro-3,4-dihydro-2h-thieno [3,2-e] - 1,2-thiazine-4-alcohol 1,1-dioxide;Ozenoxacin Impurity 7

Chemical & Physical Properties

Appearance:White powder

Assay: 99%+

Boiling point:513.7±60.0℃

Flash point:264.5℃

Density:1.27±0.1g/cm³

Pka:4.12±0.18

Application

It is an intermediate of oxefloxacin.Ozenoxacin is a new fluoroquinolone-free antibiotic developed by Ferrer for the treatment of pustular dermatitis and other skin infections by inhibiting DNA rotase and topoisomerase IV as a cream (10g, 1%) for the treatment of bacterial skin infections, including gram-positive skin and soft tissue infections. At present, the compound has successfully completed phase III clinical trials for the treatment in adults and pustular dermatitis in children, showing stronger antibacterial activity, safety and tolerability. Ozefloxacin was launched in Japan in July 2014 and approved in September 2015 for the treatment of acne and skin infections (10g, 2%, gel). The chemical synthesis circuit of oxefloxacin is long, and the following compounds are an important oxefloxacin intermediate in its synthesis process

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