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1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine CAS 74853-08-0

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Place of Origin: China

Brand Name: Sunshine

Certification: ISO,COA

Model Number: 74853-08-0

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CAS 74853-08-0 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine

,

1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine

CAS No::
74853-08-0
Appearance::
Solid Crystallization
Molecular Formula::
C16H19N3O
Molecular Weight::
269.34
EINECS NO::
616-147-4
MDL NO.::
MFCD02093082
CAS No::
74853-08-0
Appearance::
Solid Crystallization
Molecular Formula::
C16H19N3O
Molecular Weight::
269.34
EINECS NO::
616-147-4
MDL NO.::
MFCD02093082
1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine CAS 74853-08-0

Product Description:

Product Name:1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine CAS 74853-08-0

 

 

Synonyms:

(4-(4-aminophenyl)-1-piperzinyl)phenol;

[4-(4-aminophenyl)piperazin-1-yl]phenol;

Posaconazole diastereoisomer 2 (r,s,r,r);

 

 

Chemical & Physical Properties

Appearance:Solid crystallization

Assay: 98%+

Kpa:12.18±0.30

Boiling point:532.8±50.0℃

Solubility:DMSO (Slight), Methanol (Very slight, heated)

Density:1.237±0.06g/cm3

 

 

Application

(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine is the intermediate of Posaconazole.

Posaconazole can effectively prevent invasive fungal infections. At present, although the injection form of posaconazole has been approved by the FDA (approved in March 2014), its status as the main preventive drug has not changed.Posaconazole exerts its antifungal activity by inhibiting the biosynthesis of ergosterol.

 

 

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