DIETHYL DIBROMOMALONATE CAS 631-22-1

Product Description:

Product Name: DIETHYL DIBROMOMALONATE CAS NO: 631-22-1

Synonyms:

Propanedioic acid, dibromo-, diethyl ester;

Diethyl dibromomalonate;

Diethyl 2,2-dibromomalonate;

Chemical & Physical Properties:

Appearance: Colorless to yellow liquid

Assay :≥99.0%

Density: 1.68

Boiling Point: 108℃(4 torr)

Flash Point: >110℃

Refractive Index: n20/D 1.484(lit.)

Safety Information:

Safety Statements: S26-S36/37/39-S45

HS Code: 2917190090

Packing Group: III

RIDADR: UN 1760

Risk Statement: R34

Diethyl dibromomalonate can be used as intermediates in pharmaceutical synthesis.

With diethyl malonate and sodium bromide as raw materials, the reaction steps are as follows: Diethyl malonate (0.160g, 1mmol), sodium bromide (0.206g, 2mmol), cuprous bromide (0.014g, 0.1mmol), manganese acetate (1chemicalbook.89g, 7mmol) and acetic acid (10ml) were added into the reaction flask at 60℃ for reaction. TLC followed the response until complete completion; After the reaction, the crude product was separated by column chromatography (ethyl acetate: petroleum e-ther = 1:20), and the target product dibromomalonate (74% yield) was obtained.

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