4-Aminosalicylic Acid CAS 65-49-6 for Pharmaceutical Production

Product Description:

Product Name: 4-Aminosalicylic acid CAS NO: 65-49-6

Synonyms:

Benzoic acid, 4-amino-2-hydroxy-;

Aminox;

para-amino salicylic acid;

Chemical & Physical Properties:

Appearance:Colorless powder

Assay :≥99.0%

Density: 1.545 g/cm3

Boiling Point: 347℃

Melting Point: 135-145℃

Flash Point: 184.1℃

Water Solubility: 2 g/L (20 ℃)

Stability: Stable under normal temperatures and pressures.

Storage Condition: Store at 0-5℃

Safety Information:

RTECS: VO1225000

Safety Statements: S26-S37/39

HS Code: 29225000

WGK Germany: 2

RIDADR: UN 1789 8/PG 3

Risk Statements: R36/37/38

Hazard Codes: Xi,Xn,T

Hazard Declaration: H319

Caution Statements: P305 + P351 + P338

Signal Word: Warning

Symbol: GHS07

4-Aminosalicylic acid (para-aminosalicylic acid or PAS) is an antibiotic used to treat tuberculosis. This organic compound has also been use since the 1940s for the treatment of inflammatory bowel diseases (IBDs), where it has shown greater potency in ulcerative colitis and Crohn's disease. It is thought to act via NF-κB (nuclear factor-kappa B) inhibition and free radical scavenging. The closely related chemical compound 5-aminosalicylic acid, sold under the name mesalazine, also has medical uses.It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.

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