CLINDAMYCIN HYDROCHLORIDE CAS 58207-19-5

Product Description:

Product Name: CLINDAMYCIN HYDROCHLORIDE CAS NO: 58207-19-5

Synonyms:

(7S)-7-CHLORO-7-DEOXYLINCOMYCIN HYDROCHLORIDE;

(2S-TRANS)-METHYL7-CHLORO-6,7,8-TRIDEOXY-6[[(1-METHYL-4-PROPYL-2-PYRROLIDINYL)CARBONYL]AMINO]-1-THIO-L-THREO-ALPHA-D-GALACTO-OCTOPYRANOSIDE;

U-21251F;

Chemical & Physical Properties:

Appearance: White Crystalline Solid

Assay :≥99.0%

Boiling Point: 647℃ at 760 mmHg

Melting Point: 143℃

Flash Point: 345.1℃

Water Solubility: Soluble in water

Safety Information:

Safety Statements: S26-37/39

Risk Statements: R36/37/38

Hazard Code: Xi

WGK Germany: 3

RTECS: GF2275000

Hazard Class: 3

HS Code: 29419090

Clindamycin hydrochloride monohydrate is an oral protein synthesis inhibitory agent that has the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin hydrochloride monohydrate resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin hydrochloride monohydrate decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla).

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