Phthalylsulfathiazole CAS 85-73-4 for Pharmaceutical Manufacturing

Product Description:

Product Name: Phthalylsulfathiazole CAS NO: 85-73-4               

Synonyms:

N-(4-thiazol-2-ylsulfamoyl-phenyl)-phthalamic acid;

Benzoic acid, 2-[[[4-[(2-thiazolylamino)sulfonyl]phenyl]amino]carbonyl]-;

2-[({4-[(2-thiazolylamino)sulfonyl]phenyl}amino)carbonyl]-benzoic acid;

Chemical & Physical Properties:

Appearance: White or yellowish-white, crystalline powder

Assay :≥99.0%

Density: 1.596 g/cm3

Boiling Point: 579℃ at 760 mmHg

Melting Point: 198-204℃

Flash Point: 304℃

Storage Temp.: -20℃

Solubility: Practically insoluble in water, freely soluble in dimethylformamide, slightly soluble in aceton/e and in ethanol (96 per cent).

Safety Information:

RTECS: TH8575000

Hazard Class: 6.1(b)

HS Code: 2935009090

Packing Group: III

RIDADR: UN 3249

Phthalylsulfathiazole is a sulfonamides antimicrobial agent with similar but strong effects to sulfonamides and sulfothiazoles. It is rarely absorbed by oral administration and slowly decomposes in the intestine to release sulfathiazoles, thus playing an antibacterial role in the intestinal tract. It is clinically used for enteritis, bacterial dyrazole and intestinal preoperation preparation. People allergic to sulfonamides should not use it. Hydrolysis in the intestinal tract, so that the amino free, can play a bacteriostatic effect. It belongs to broad - spectrum and slow - acting bacteriostatic drug. The antibacterial effect in large intestine is stronger than that of SG, which is 2-4 times more than that of SST. Sulfonamides. For pullorum, pullorum, paratyphoid fever. It's an intestinal anti-inflammatory. For gastrointestinal bacterial infection, bacterial dysentery, bacterial ulcerative enteritis can also be used for intestinal surgery after the prevention of infection.

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