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Home > products > Pharmaceutical Intermediates > 5-Fluoro-2-oxindole CAS 56341-41-4

5-Fluoro-2-oxindole CAS 56341-41-4

Product Details

Place of Origin: China

Brand Name: Sunshine

Certification: ISO,COA

Model Number: 56341-41-4

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Packaging Details: Aluminum Foil Bag, Drum

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Highlight:
CAS NO::
56341-41-4
Appearance::
Light Yellow Crystalline
Molecular Formula::
C8H6FNO
Molecular Weight::
151.13800
EINECS NO::
638-803-9
MDL NO::
MFCD02179598
CAS NO::
56341-41-4
Appearance::
Light Yellow Crystalline
Molecular Formula::
C8H6FNO
Molecular Weight::
151.13800
EINECS NO::
638-803-9
MDL NO::
MFCD02179598
5-Fluoro-2-oxindole CAS 56341-41-4

Product Description:

Product Name: 5-Fluoro-2-oxindole CAS NO: 56341-41-4


Synonyms:

Fluorooxindole;

5-fluoro-2-oxo-1,2-dihydro-indole;

5-fluoroindolin-2-one;


Chemical & Physical Properties:

Appearance: Light yellow crystalline

Assay :≥99.00%

Density: 1.311 g/cm3

Boiling Point: 307.2℃ at 760 mmHg

Melting Point: 143-147℃

Flash Point: 139.6℃

Refractive Index: 1.56

Storage Condition: Keep Cold


Safety Information:

Safety Statements: S22-S24/25

HS Code: 2933990090

WGK Germany: 3

Risk Statements: R36/37/38

Hazard Codes: Xi; C


5- fluorindole-2 - one is an organic ketone, which can be used as an intermediate in the preparation of Sunitinib. First, 4-fluoroaniline was used as the starting material to react with chloral hydrate and hydroxylamine hydrochloride to form p-fluoroisonitroacetanilide. Then, 5-fluorindole-2-one was formed by cyclization under the action of concentrated sulfuric acid. Finally, 5-fluoroindole-2-one was obtained by the reaction of Wolff-Kishner-Huangming long with a total yield of 66%.


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