Tirofiban Hydrochloride Monohydrate CAS 150915-40-5

Product Description:

Product Name: Tirofiban hydrochloride monohydrate CAS NO: 150915-40-5

Synonyms:

L 700462 MK 383 N-(butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L-tyrosine;

(2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acid,hydrate,hydrochloride;

Tirofiban hydrochloride monohydrate;

Chemical & Physical Properties:

Appearance: White solid

Assay :≥99.00%

Boiling Point: 611.7℃ at 760 mmHg

Melting Point: 135-137℃

Flash Point: 323.7℃

Storage Condition: -20℃ Freezer

Water Solubility: DMSO: >12mg/mL at warmed to 60℃

Safety Information:

Hazard Code: Xi

Risk Statements: R36/37/38

Safety Statements: S26-37-45

WGK Germany: 3

Symbol: GHS07

Signal Word: Warning

Hazard Statements: H315-H319-H335

Precautionary Statements: P261-P305 + P351 + P338

Tirofiban is a specific nonpeptide platelet fibrinogen receptor (GPIIb/IIIa) antagonist. Tirofiban is an antithrombotic used in the treatment of unstable angina. Tirofiban hydrochloride monohydrate is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonistIC50 value:Target: integrin IIb/IIIa Tirofiban hydrochloride monohydrate blocks platelet aggregation and thrombus formation. Tirofiban is an antithrombotic used in the treatment of unstable angina.Tirofiban, in a concentration-dependent manner reduced platelet aggregation evoked by ADP (IC50 approximately 70 ng/ml), collagen (IC50 approximately 200 ng/ml), and thrombin (IC50 approximately 5,000 ng/ml).

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