7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one CAS 137982-91-3

Product Description:

Product Name: 7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one CAS NO: 137982-91-3

Synonyms:

7-chloro-1-(2-methyl-4-nitrobenzoyl)-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine;

7-Chloro-1-(2-methyl-4-nitrobenzoyl)-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one;

1H-benzo[b]azepine;

Chemical & Physical Properties:

Appearance: White to off-white solid

Assay :≥99.00%

Density: 1.387

Boiling Point: 573.345℃ at 760 mmHg

Flash Point: 300.548℃

Vapor Pressure: 0.0±1.6 mmHg at 25℃

Index of Refraction: 1.635

Storage: Refrigerator, under inert atmosphere

Solubility: DMSO (Slightly), Methanol (Slightly)

Safety Information:

HS Code: 2933990090

7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one is an intermediate in synthesizing Tolvaptan-d7 (T536652), a labelled Tolvaptan (T536650). It is a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).

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