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Home > products > Pharmaceutical Intermediates > (2R,3S)-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}-3-(4-FLUOROPHENYL)MORPHOLINE HYDROCHLORIDE CAS 171482-05-6

(2R,3S)-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}-3-(4-FLUOROPHENYL)MORPHOLINE HYDROCHLORIDE CAS 171482-05-6

Product Details

Place of Origin: China

Brand Name: Sunshine

Certification: ISO,COA

Model Number: 171482-05-6

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Packaging Details: Aluminum Foil Bag, Drum

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CAS 171482-05-6

,

(2R

,

3S)-2-{(1R)-1-[3

,

5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}-3-(4-FLUOROPHENYL)MORPHOLINE HYDROCHLORIDE

Appearance::
White To Off-white Solid
CAS NO::
171482-05-6
Molecular Formula::
C20H19ClF7NO2
Molecular Weight::
473.81200
EINECS NO::
691-262-0
MDL NO::
MFCD13183776
Appearance::
White To Off-white Solid
CAS NO::
171482-05-6
Molecular Formula::
C20H19ClF7NO2
Molecular Weight::
473.81200
EINECS NO::
691-262-0
MDL NO::
MFCD13183776
(2R,3S)-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}-3-(4-FLUOROPHENYL)MORPHOLINE HYDROCHLORIDE CAS 171482-05-6

Product Description:

Product Name:

(2R,3S)-2-{(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY}-3-(4-FLUOROPHENYL)MORPHOLINE HYDROCHLORIDE CAS NO: 171482-05-6


Synonyms:

(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride (1:1);

Aprepitant HCl;

Aprepitant M2 Metabolite (1R, 2R, 3S);


Chemical & Physical Properties:

Appearance: White to off-white solid

Assay :≥99.00%

Boiling Point: 387.9℃ at 760 mmHg

Flash Point: 188.4℃


5-[[(2R, 3S) -2-[(1R) -1-[3, 5-bis (trifluoromethyl) phenyl] ethoxy]-3- (4-fluorophenyl) -4-morphoryl] methyl]-1, 2-dihydro-3H-1, 2, chemicalbook4-triazol-3-ketone It is an antiemetic drug developed by Merck in the United States for the prevention of acute and delayed vomiting during chemotherapy. Clinical studies have shown that adjuvant administration of aprepitant can significantly control chemotherapy-induced nausea and vomiting (CINV) symptoms in the use of moderate and highly emetic chemotherapy drugs.


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