![Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate CAS 1235865-75-4](/images/load_icon.gif){kind=icon}
![Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate CAS 1235865-75-4](/photo/pl205886699-methyl_4_fluoro_2_1h_pyrrolo_2_3_b_pyridin_5_yloxy_benzoate_cas_1235865_75_4.jpg)
Product Details
Place of Origin: China
Brand Name: Sunshine
Certification: ISO,COA
Model Number: 1235865-75-4
Payment & Shipping Terms
Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: Aluminum Foil Bag, Drum
Delivery Time: 7-15DAY
Payment Terms: L/C,D/A,D/P,T/T,Western Union,MoneyGram
Supply Ability: G,KG,TON
Appearance:: |
White To Off-white Powder |
CAS NO:: |
1235865-75-4 |
Molecular Formula:: |
C15H11FN2O3 |
Molecular Weight:: |
286.25800 |
EINECS NO:: |
833-812-6 |
MDL NO:: |
MFCD28129691 |
Appearance:: |
White To Off-white Powder |
CAS NO:: |
1235865-75-4 |
Molecular Formula:: |
C15H11FN2O3 |
Molecular Weight:: |
286.25800 |
EINECS NO:: |
833-812-6 |
MDL NO:: |
MFCD28129691 |
Product Description:
Product Name: Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate CAS NO: 1235865-75-4
Synonyms:
methyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate;
ABT199 intermediate 3;ABT199 intermediates;
ABT-199 Intermediate;
Chemical & Physical Properties:
Appearance: White to off-white powder
Assay :≥99.00%
Density: 1.377±0.06 g/cm3(Predicted)
Pka: 13.21±0.40(Predicted)
Boiling Point:444.0±45.0℃ at 760 mmHg
Flash Point: 222.3±28.7℃
Vapor Pressure: 0.0±1.1 mmHg at 25℃
Index of Refraction: 1.640
Safety Information:
Signal Word: Warning
Precautionary Statements: P261-P305+P351+P338
Hazard Statements: H302-H315-H319-H335
Methyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate is an intermediate of ABT 199, a potent and selective Bcl-2 inhibitor with strong antitumor activity while preserving platelets. Its practical use is in the treatment of chronic lymphocytic leukemia cells and e-strogen receptor positive breast cancer.
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