2-[(4-m-ethoxy-3-methyl-pyridin-2-yl)methylsulfinyl]-5-pyrrol-1-yl-3H-benzoimidazole CAS 172152-36-2

Product Description:

Product Name:

2-[(4-m-ethoxy-3-methyl-pyridin-2-yl)methylsulfinyl]-5-pyrrol-1-yl-3H-benzoimidazoleCASNO: 172152-36-2

Synonyms:

Aldenon;

2-{[(4-m-ethoxy-3-methylpyridin-2-yl)methyl]sulfinyl}-6-(1h-pyrrol-1-yl)-1h-benzimidazole;

Ilaprazole [INN];

Chemical & Physical Properties:

Appearance: Pale grey to light grey solid

Assay :≥99.00%

Density: 1.39g/cm3

Boiling Point: 651℃ at 760 mmHg

Flash Point: 347.5℃

Refractive Index: 1.71

Vapor Pressure: 7.87E-17mmHg at 25℃

Storage: -20℃ Freezer

Solubility: Dichloromethane (Slightly), DMSO (Slightly), Methanol (Slightly)

Ilaprazole (trade name Noltec) is a proton pump inhibitor (PPI) used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. It is available in strengths of 5, 10, and 20mg.

Clinical studies show that ilaprazole is at least as potent a PPI as omeprazole when taken in equivalent doses. Studies also showed that ilaprazole significantly prevented the development of reflux oesophagitis.

Ilaprazole is developed by Il-Yang Pharmaceutical (Korea), and is still under clinical trials with US FDA. It has launched in Korea and China for the treatment of gastric ulcer, duodenal ulcer, gastroesophageal reflux disease and erosive esophagitis.

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