Dabigatran Ethyl Ester CAS 429658-95-7

Product Description:

Product Name: Dabigatran ethyl ester CAS NO: 429658-95-7

Synonyms:

Ethyl3-(2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate;

N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-beta-alanine ethyl ester;

Chemical & Physical Properties:

Appearance: Powder

Assay :≥99.00%

Density: 1.31

Boiling Point: 774.5℃ at 760 mmHg

PKa: 12.92±0.50(Predicted)

Flash Point: 413.1±35.7℃

Vapor Pressure: 0.0±2.6 mmHg at 25℃

Index of Refraction: 1.658

Dabigatran Ethyl Ester, is a derivative of Dabigatran, acting as nonpeptide, direct thrombin inhibitor. Antithrombotic. ethyl ester of Dabigatran, which is an emerging oral anticoagulant which is a direct inhibitor of thrombin activity. IC50 value:Target: thrombinDabigatran provides a stable anticoagulation effect without any need to perform periodical laboratory controls. Of note, there is a growing amount of clinical evidence which shows its safety and efficacy. For these reasons, Dabigatran may suppose a revolution in oral anticoagulation. Dabigatran etexilate was rapidly converted to Dabigatran, with peak plasma dabigatran concentrations being attained after approximately 1.5 h; the bioavailability of Dabigatran after p.o. administration of Dabigatran etexilate was 7.2%.

If you are interested in our products or have any questions, please feel free to contact us!

Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.