Dinoprost Prostaglandin F2α Tromethamine Salt CAS 38562-01-5

Product Description:

Product Name: Dinoprost Prostaglandin F2α Tromethamine Salt CAS NO: 38562-01-5            

Synonyms:

Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, (5Z,9α,11α,13E,15S)-, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1);

Prostaglandin F2α-tham;

Prostaglandin F2α tris(hydroxymethyl)aminomethane;

Chemical & Physical Properties:

Appearance: White solid

Assay :≥99.00%

Boiling Point: 531℃ at 760 mmHg

Melting Point: 25-35℃

Flash Point: 289℃

Storage Condition: -20℃

Solubility: H2O: 1 mg/mL Aqueous solutions are stable for 30 days at 2-8℃ and for several months frozen at −0℃ in single use aliquots. Avoid repeated freeze/thaw cycles.

Safety Information:

Safety Statements: S53-45

HS Code: 2937500000

Risk Statements: R60; R22

Hazard Code: T

Hazard Declaration: H302; H360

Signal Word: Danger

Symbols: GHS07, GHS08

Caution Statements: P201; P308 + P313

Prostaglandin F2α (PGF2α in prostanoid nomenclature), pharmaceutically termed dinoprost (INN), is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.

In domestic mammals, it is produced by the uterus when stimulated by oxytocin, in the event that there has been no implantation during the follicular phase. It acts on the corpus luteum to cause luteolysis, forming a corpus albicans and stopping the production of progesterone. Action of PGF2α is dependent on the number of receptors on the corpus luteum membrane.

The PGF2α isoform 8-iso-PGF2α was found in significantly increased amounts in patients with endometriosis, thus being a potential causative link in endometriosis-associated oxidative stress.

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