Ethyl1-(4-m-ethoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylate CAS 536759-91-8

Product Description:

Product Name:

Ethyl1-(4-m-ethoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylate CAS NO: 536759-91-8 

Synonyms:

4,5,6,7-Tetrahydro-1-(4-m-ethoxyphenyl)-6-(4-nitrophenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester;

1H-Pyrazolo[3,4-c]pyridine-3-carboxylicacid,4,5,6,7-tetrahydro-1-(4-M-ethoxyphenyl)-6-(4-nitrophenyl)-7-oxo-,ethylester;

Apixaban iMpurityG;

Chemical & Physical Properties:

Appearance: Pale brown to light orange solid

Assay :≥99.00%

Density: 1.4

Melting Point: 190-192℃

Flash Point: 352.2±31.5℃

Boiling Point: 658.75℃ at 760 mmHg

Refractive Index: 1.661

Vapor Pressure: 0.0±2.0 mmHg at 25℃

Safety Information:

Signal Word: Warning     

Precautionary Statements: P261-P305+P351+P338       

Hazard Statements: H302-H315-H319-H335

Ethyl1-(4-M-ethoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate is an intermediate in the synthesis of Apixaban, a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation

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