Bazedoxifene Acetate CAS 198481-33-3 for Pharmaceutical

Product Description:

Product Name: Bazedoxifene acetate CAS NO: 198481-33-3

Synonyms:

acetic acid,1-[[4-[2-(azepan-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methylindol-5-ol;

1-(p-(2-(Hexahydro-1H-azepin-1-yl)ethoxy)benzyl)-2-(p-hydroxyphenyl)-3-methylindol-5-ol monoacetate (salt);

Unii-J70472ud3d;

Chemical & Physical Properties:

Appearance: White to beige powder

Assay :≥99.0%

Boiling Point: 694.4℃ at 760 mmHg

Flash Point: 373.8℃

Vapor Pressure: 6.33E-20mmHg at 25℃

Safety Information:

WGK Germany: 3

Bazedoxifene Acetate is a nonsteroidal selective e-strogen receptor modulator (SERM). Bazedoxifene Acetate is used as an antiosteoporotic. The selective e-strogen receptor modulator bazedoxifene acetate was approved in Spain for the treatment of osteoporosis in postmenopausal women. The drug was discovered by Wyeth (now Pfizer) and licensed to Almirall. Clinical trials with bazedoxifene along with conjugated es-trogens demonstrated significant improvement in bone mineral density and prevented bone loss in postmenopausal women without osteoporosis. It also reduces fracture risks among women with postmenopausal osteroporosis.

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