Esomeprazole Magnesium Trihydrate CAS 217087-09-7

Product Description:

Product Name: Esomeprazole magnesium trihydrate CAS NO: 217087-09-7                                 

Synonyms:

Esomeprazole magnesium;

(S)-Omeprazole magnesium trihydrate;

5-m-ethoxy-2-[(4-m-ethoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]benzimidazol-1-ide;

Chemical & Physical Properties:

Appearance: Off-white powder

Assay :≥99.0%

Boiling Point: 600℃ at 760 mmHg

Melting Point: 184-189℃ (dec.)

Flash Point: 316.7℃

Vapor Pressure: 2.35E-14mmHg at 25℃

StorageTemp: -20℃ Freezer

Solubility: Slightly soluble in water, soluble in methanol, practically insoluble in heptane.     

Safety Information:

Hazard Code:  Xn

Risk Statements: R22

WGK Germany: 3

HS Code:  2933399090

S-Form of Omeprazole. Gastric proton-pump inhibitor.

esomeprazole magnesium trihydrate for the healing of peptic ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy.

Zollinger-Ellison syndrome

Peptic ulcer, site unspecified

Duodenal ulcer

Gastric ulcer

Gastro-oesophageal reflux disease

Esomeprazole belongs to the family of medications known as proton pump inhibitors (PPIs). Esomeprazole is registered by the Therapeutic Goods Administration (TGA) for the following indications:

Gastro-Oesophageal Reflux Disease (GORD):

treatment of erosive reflux oesophagitis;

long-term management of patients with healed oesophagitis to prevent relapse;

symptomatic treatment of gastro-oesophageal reflux disease (GORD).

In combination with appropriate antibiotics for:

healing of duodenal ulcer associated with Helicobacter pylori;

eradication of Helicobacter pylori in patients with active or healed peptic ulcer.

Short-term treatment of upper gastrointestinal symptoms associated with non-steroidal anti-inflammatory drug (NSAID) (non-selective and COX-2 selective) therapy.

Healing of gastric ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy.

Prevention of gastric and duodenal ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy in patients at risk.

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