Imatinib Mesylate CAS 220127-57-1 for Medicinal Treatment

Product Description:

Product Name: Imatinib Mesylate CAS NO: 220127-57-1                                      

Synonyms:

[Imantinib mesylate];

Gleevac;

4-[(4-Methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide methanesulfonate;

Chemical & Physical Properties:

Appearance: White crystalline powder

Assay :≥99.0%

Density: 0.858 g/mL at 25 ℃ (lit.)

Boiling Point: 754.9℃ at 760 mmHg

Flash Point: 410.3℃

Refractive Index: n20/D 1.401(lit.)

Melting Point: 214-224℃

Safety Information:

HS Code: 2933990090

WGK Germany: 3

Hazard Declaration: H302

Symbol: GHS07

Signal Word: Warning

Hazard Code: Xn

A tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL).

Imatinib Mesylate is orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively. Imatinib also known as Gleevec, Glivec, CGP-57148B, STI-571 & Imatinib.

Imatinib Mesylate (STI571) is an orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively.

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