Risedronate Sodium CAS 115436-72-1 for Improved Bone Density

Product Description:

Product Name: Risedronate Sodium CAS NO: 115436-72-1                                             

Synonyms:

3-Pyridyl-1-hydroxyethylidene-1,1-biphosphonic acid sodium salt;

Phosphonic acid, P,P'-[1-hydroxy-2-(3-pyridinyl)ethylidene]bis-, sodium salt (1:1);

sodium hydrogen-1-hydroxy-1-phosphono-2-(pyridin-3-yl)ethylphosphonate;

Chemical & Physical Properties:

Appearance: Fine white to off-white crystalline powder

Assay :≥98.0%

Boiling Point: 692.3℃ at 760 mmHg

Flash Point: 372.5℃

Vapor Pressure: 4.03E-20mmHg at 25℃

Storage Temp.: Store at RT

Solubility: H2O: soluble5mg/mL, clear (warmed)

Safety Information:

Hazard Declaration: H302 + H312 + H332

Caution Statement: P280

Symbol: GHS07

Signal Word: Warning

Risedronic acid (INN) often used as its sodium salt risedronate sodium (USAN) is a bisphosphonate used to strengthen bone, treat or prevent osteoporosis, and treat Paget's disease of bone. It is produced and marketed by Warner Chilcott, Sanofi-Aventis, and in Japan by Takeda under the trade names Actonel, Atelvia, and Benet. It is also available in a preparation that includes a calcium carbonate supplement, as Actonel with Calcium. Risedronic Acid is a pyridinyl biphosphonate bone resorption inhibitor. Risedronate sodium is a pyridinyl biphosphonate which inhibits osteoclast-mediated bone resorption.Target: Risedronate sodium, which was promoted in Croatia a few months ago, is the latest (III) generation of bisphosphonates, the most efficient anti-resorption drugs that inhibit osteoclast-mediated bone resorption and change the bone metabolism. Risedronate sodium is hence the first line of bisphosphonates for the reduction of vertebral and non-vertebral fracture risks in postmenopausal women with osteoporosis or those with a high risk of osteoporosis.

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