Product Details
Place of Origin: China
Brand Name: Sunshine
Certification: ISO,COA
Model Number: 1802998-75-9
Payment & Shipping Terms
Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: Aluminum Foil Bag, Drum
Delivery Time: 7-15 days
Payment Terms: L/C,D/A,D/P,T/T,Western Union
Supply Ability: TON
CAS No:: |
1802998-75-9 |
Appearance:: |
White To Pale Yellow Powder |
Molecular Formula:: |
C25H27N5O7S |
Molecular Weight:: |
541.58 |
EINECS NO:: |
848-707-0 |
MDL NO.:: |
N/A |
CAS No:: |
1802998-75-9 |
Appearance:: |
White To Pale Yellow Powder |
Molecular Formula:: |
C25H27N5O7S |
Molecular Weight:: |
541.58 |
EINECS NO:: |
848-707-0 |
MDL NO.:: |
N/A |
Product Description:
Filgotinib maleate CAS 1802998-75-9
Synonyms:
N-(5-(4-((1,1-Dioxidothiomorpholino)methyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide maleate;
Cyclopropanecarboxamide,N-(5-(4-((1,1-dioxido-4-thiomorpholinyl)methyl)phenyl)(1,2,4)triazolo(1,5-a)pyridin-2-yl)-,(2Z)-2-butenedioate (1:1);
(Z)-but-2-enedioic acid;N-[5-[4-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;
Chemical & Physical Properties
Appearance: White to pale yellow powder
Assay: NLT99%
Melting Point: 225-231 ℃(lit.)
Application: Filgotinib (maleate) is a selective and orally active JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM and 116 nM for JAK1, JAK2, JAK3 and TYK2, respectively. Filgotinib (maleate) can be used for rheumatoid arthritis (RA) and Crohn's disease research.
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