Sacubitril Sodium Salt CAS 149690-05-1

Product Description:

Product Name: Sacubitril Sodium Salt CAS NO:149690-05-1

Synonyms:

sodium,4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate;

(1,1'-Biphenyl)-4-pentanoic acid, gamma-((3-carboxy-1-oxopropyl)amino)-alpha-methyl-, 4-ethyl ester, sodium salt (1:1), (alphar,gammas)-;

Chemical & Physical Properties

Appearance : Almost white powder

Assay : ≥99.0%

Vapor Pressure: 0.0mmHg at 25°C

PSA: 99.02000

LogP: 4.54780

Solubility: 10mM in DMSO.

Category: Standards; Pharmaceutical/API Drug Impurities/Metabolites;

Safety Information

HS Code: 2933990090

Storage:Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

Application:

Sacubitril Sodium is used in the synthesis of LCZ696 ; Intermediate of LCZ696.

Lcz696 intermediate is a double acting angiotensin receptor enkephalinase inhibitor with a unique mode of action, which is believed to reduce the strain of exhaustion. Some analysts predict that lcz696 will peak at $8 billion, while deutsche bank analysts expect the drug to peak at $6 billion, given its superior performance in reducing key cardiovascular risks. There is no doubt that lcz696 will become a superstar, although there are some differences in the data.

Our factory manufacture’s Sacubitril Sodium Salt CAS 149690-05-1 , mature technology, stable output, quality assurance.

Inventory Status : In Stock.

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