Lenvatinib CAS 417716-92-8

Product Description:

Product Name: lenvatinib CAS NO: 417716-92-8

Synonyms:

E7080,E 7080;

Lenvatinib (E7080);

4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-methoxyquinoline-6-carboxamide;

Chemical & Physical Properties:

Appearance: White to off-white solid powder

Assay: ≥98.0%

Density: 1.469g/cm3

Boiling Point: 627.242℃ at 760 mmHg

Flash Point: 333.144℃

Refractive Index: 1.697

Solubility: Soluble in DMSO

Storage condition: Short term storage (weeks): 0 – 4℃ under dry condition; Long term storage (months): -20 ℃under dry condition

Safety Information:

Hazard Statements: Causes serious eye irritation. Suspected of damaging fertility or the unborn child

Precautionary Statements General: Keep out of reach of children.

Lenvatinib (trade name Lenvima) is an anti-cancer drug for the treatment of certain kinds of thyroid cancer, and potentially for other cancers as well. It was developed by Eisai Co. and acts as a multiple kinase inhibitor against the VEGFR1, VEGFR2 and VEGFR3 kinases. E7080 (Lenvatinib) is a multi-target inhibitor of VEGFR2 and VEGFR3 with IC50 of 4 nM and 5.2 nM, respectively.

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