Product Details
Place of Origin: China
Brand Name: Sunshine
Certification: ISO,COA
Model Number: 641571-10-0
Payment & Shipping Terms
Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: Aluminum Foil Bag, Drum
Delivery Time: 7-15 days
Payment Terms: T/T, L/C, D/A, Western Union
Supply Ability: TON
CAS NO:: |
641571-10-0 |
Appearance:: |
Off-White Solid |
Molecular Formula:: |
C28H22F3N7O |
Molecular Weight:: |
529.516 |
EINECS NO:: |
700-544-5 |
MDL NO:: |
MFCD09833716 |
CAS NO:: |
641571-10-0 |
Appearance:: |
Off-White Solid |
Molecular Formula:: |
C28H22F3N7O |
Molecular Weight:: |
529.516 |
EINECS NO:: |
700-544-5 |
MDL NO:: |
MFCD09833716 |
Product Description:
Product Name: nilotinib CAS NO: 641571-10-0
Synonyms:
Nilotinib (AMN-107);
its intermediates;
Nilotinib for research;
Chemical & Physical Properties:
Appearance: Off-White Solid
Assay: ≥99.0%
Density: 1.36 g/cm3
Refractive Index: 1.65
Storage Temp.:-20℃ Freezer
Melting point: 231-233℃
Safety Information:
Hazard Class: 6.1(b)
Packing Group: III
RIDADR: 2206
Nilotinib (AMN107, trade name Tasigna), in the form of the hydrochloride monohydrate salt, is a small-molecule tyrosine kinase inhibitor approved for the treatment of imatinib-resistant chronic myelogenous leukemia. Structurally related to imatinib, it was developed based on the structure of the Abl-imatinib complex to address imatinib intolerance and resistance. Nilotinib is a selective Bcr-Abl kinase inhibitor that is 10-30 fold more potent than imatinib in inhibiting Bcr-Abl tyrosine kinase activity and proliferation of Bcr-Abl expressing cells.
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