Cabazitaxel CAS NO: 183133-96-2

Product Description:

Product Name: Cabazitaxel CAS NO: 183133-96-2

Synonyms:

Jevtana;

CABAZITAXEL;

Cabazitaxelum;

Taxoid XRP6258;

TXD258;

XRP-6258;

(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-(acetyloxy)-15-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy-3-phenylpropanoyl]oxy}-1-hydroxy-9,12-dimet hoxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04'7]heptadec-13-en-2-ylbenzoate;

Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4,6-dimet hoxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2aα,4β,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,12bα]]-;

Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4,6-dimet hoxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1Hcyclodeca[3,4]benz[1,2-b]oxet-9-ylester, (αR,βS)-;;

Chemical & Physical Properties:

Appearance : White Powder

Assay : ≥99.0% USP/GMP/DMF

Density:1.3±0.1 g/cm3

Boiling Point:870.7±65.0 °C at 760 mmHg

Flash Point:480.4±34.3 °C

PSA: 202.45000

LogP :7.55

Vapour Pressure:0.0±0.3 mmHg at 25°C

Index of Refraction: 1.592

Applications: Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.

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