10-DAT, Deacetyltaxol CAS 78432-77-6

Product Description:

Product Name: 10-DAT, Deacetyltaxol CAS NO: 78432-77-6

Synonyms:

7-epi-10-deacetyltaxol;

b-(Benzoylamino)-a-hydroxy-benzenepropanoic acid [2aR-[2aa,4b,4ab,6b,9a(aR*,bS*),11a,12a,12aa,12ba]]-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester;

7-EPI-10-DEACETYL PACLITAXEL;

10-DEACETYLTAXOL;

10-Desacetyl Paclitaxel;

10-Desacetyltaxol;

10-Deacetylpaclitaxel;

Chemical & Physical Properties:

Appearance : white or off-white powder

Assay : ≥99.0%,

Density                      1.41 g/cm3

Boiling Point              959.5ºC at 760 mmHg

Melting Point             182-184ºC

Flash Point                 534.1ºC

Refractive Index         1.652

10-Deacetyltaxol (10-Deacetylpaclitaxel) is a taxane derivative isolated from Taxus wallichiana Zucc[1]. 10-Deacetyltaxol (10-Deacetylpaclitaxel) promotes the polymerization of tubulin and to inhibit the depolymerization of microtubules induced by cold or by calcium ions in vitro[2]. 10-Deacetyltaxol (10-Deacetylpaclitaxel) exhibits cytotoxicity in human glial and neuroblastoma cell-lines[3].

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